Paralogue Annotation for RYR2 residue 355

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 355
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 355

No paralogue variants have been mapped to residue 355 for RYR2.

RYR2	AFTFRS---SKEKLDVGVRKEVDGMGTSEI>K<YGDSVCYIQHVDTGLWLTYQSVDVKSVRMG	385
RYR1	SFCFRI---SKEKLDVAPKRDVEGMGPPEI>K<YGESLCFVQHVASGLWLTYAAPDPKALRLG	369
RYR3	AFSFRASKELKEKLDSSHKRDIEGMGVPEI>K<YGDSVCFVQHIASGLWVTYKAQDAKTSRLG	377
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.K355E	c.1063A>G	Putative Benign		rs267598432	SIFT: deleterious Polyphen: probably damaging