Paralogue Annotation for RYR2 residue 3659

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3659
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 3659

No paralogue variants have been mapped to residue 3659 for RYR2.

RYR2	ETEEHYFEDKLIEDLAKPG-AEPPEEDEGT>K<RVDPLHQLILLFSRTALTEKCKLEEDFLYM	3689
RYR1	LTEDHSFEDRMIDDLSKAGEQEEEEEEVEE>K<KPDPLHQLVLHFSRTALTEKSKLDEDYLYM	3723
RYR3	ETEEYSFEEKLVQDLAKSPKVEEEEEEETE>K<QPDPLHQIILYFSRNALTERSKLEDDPLYT	3578
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.K3659Q	c.10975A>C	Putative Benign		rs184527312	SIFT: tolerated Polyphen: possibly damaging
p.K3659E	c.10975A>G	Putative Benign			SIFT: Polyphen: