Paralogue Annotation for RYR2 residue 3985

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3985
Reference Amino Acid: M - Methionine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3985

No paralogue variants have been mapped to residue 3985 for RYR2.



RYR2QMKLSQDSSQIELLKELMDLQKDMVVMLLS>M<LEGNVVNGTIGKQMVDMLVESSNNVEMILK4015
RYR1MMKLAQDSSQIELLKELLDLQKDMVVMLLS>L<LEGNVVNGMIARQMVDMLVESSSNVEMILK4059
RYR3QMKLSQDSSQIELLKELLDLLQDMVVMLLS>L<LEGNVVNGTIGKQMVDTLVESSTNVEMILK3911
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Met3985Lysc.11954T>A UnknownSIFT:
Polyphen: