Paralogue Annotation for RYR2 residue 4231

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4231
Reference Amino Acid: P - Proline
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 4231

No paralogue variants have been mapped to residue 4231 for RYR2.



RYR2ISESDLNERSANKEESEK-----ERPEEQG>P<RMAFFSILTVRSALFALRYNILTLMRMLSL4261
RYR1ISEPEGEPETDEDEGAGAAEAGAEGAEEGA>A<GLEGTAATAAAGATARVVAAAGRALRGLSY4310
RYR3ISESDSADRPEEEEEDEDSSYVLEIAGEEE>E<DGSLEPASAFAMACASVKRNVTDFLKRATL4162
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P4231Qc.12692C>A UnknownSIFT:
Polyphen: benign