Paralogue Annotation for RYR2 residue 424

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 424
Reference Amino Acid: F - Phenylalanine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 424

No paralogue variants have been mapped to residue 424 for RYR2.



RYR2HHEGHMDDGISLSRSQHEESRTARVIRSTV>F<LFNRFIRGLDALSKKAKA----STVDLPIE450
RYR1HQEGHMDDALSLTRCQQEESQAARMIHSTN>G<LYNQFIKSLDSFSGKPRGSGPPAGTALPIE438
RYR3HQEGHMDDGLTLQRCQREESQAARIIRNTT>A<LFSQFVSGN-----NRTA----APITLPIE437
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.F424Lc.1272C>G Putative BenignSIFT:
Polyphen: