Paralogue Annotation for RYR2 residue 4306

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4306
Reference Amino Acid: F - Phenylalanine
Protein Domain: Transmembrane region

Paralogue Variants mapped to RYR2 residue 4306

No paralogue variants have been mapped to residue 4306 for RYR2.

RYR2	VKDMVTAFFSSYWSIFMTLLHFVASVFRGF>F<RIICSLLLGGSLVEGAKKIKVAELLANMPD	4336
RYR1	AREAATAVAALLWAAVTRAGAAGAGAAAGA>L<GLLWGSLFGGGLVEGAKKVTVTELLAGMPD	4385
RYR3	AKELVKVLFSFFWMLFVGLFQLLFTILGGI>F<QILWSTVFGGGLVEGAKNIRVTKILGDMPD	4237
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.F4306S	c.12917T>C	Putative Benign			SIFT: Polyphen: