Paralogue Annotation for RYR2 residue 4341

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4341
Reference Amino Acid: E - Glutamate
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4341

No paralogue variants have been mapped to residue 4341 for RYR2.



RYR2SLLLGGSLVEGAKKIKVAELLANMPDPTQD>E<VRGDGEEGERKP-LEAALPSEDLTDLKELT4370
RYR1GSLFGGGLVEGAKKVTVTELLAGMPDPTSD>E<VHGEQPAGPGGDADGEGASEGAGDAAEGAG4420
RYR3STVFGGGLVEGAKNIRVTKILGDMPDPTQF>G<IHDDTMEAERAEVMEPGITTELVHFIKGEK4272
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E4341Ac.13022A>C Putative BenignSIFT:
Polyphen: