Paralogue Annotation for RYR2 residue 435

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 435
Reference Amino Acid: A - Alanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 435

No paralogue variants have been mapped to residue 435 for RYR2.

RYR2	LSRSQHEESRTARVIRSTVFLFNRFIRGLD>A<LSKKAKA----STVDLPIESVSLSLQDLIG	461
RYR1	LTRCQQEESQAARMIHSTNGLYNQFIKSLD>S<FSGKPRGSGPPAGTALPIEGVILSLQDLII	449
RYR3	LQRCQREESQAARIIRNTTALFSQFVSGN->-<---NRTA----APITLPIEEVLQTLQDLIA	448
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A435V	c.1304C>T	Putative Benign			SIFT: Polyphen: