Paralogue Annotation for RYR2 residue 4377

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4377
Reference Amino Acid: S - Serine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4377

No paralogue variants have been mapped to residue 4377 for RYR2.



RYR2EGERKP-LEAALPSEDLTDLKELTEESDLL>S<D-----IFGLDLKREGGQYKLIPHNPNAGL4402
RYR1AGPGGDADGEGASEGAGDAAEGAGDEEEAV>H<EAGPGGADGAVAVTDGGPFRPEGAGGLGDM4457
RYR3EAERAEVMEPGITTELVHFIKGEKGDTDIM>S<D-----LFGLHPKKEGS-LKHGPEVGLGDL4303
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Ser4377Leuc.13130C>T UnknownSIFT:
Polyphen: