Paralogue Annotation for RYR2 residue 4400

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4400
Reference Amino Acid: A - Alanine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4400

No paralogue variants have been mapped to residue 4400 for RYR2.



RYR2LLSD-----IFGLDLKREGGQYKLIPHNPN>A<GLSDLMSN-PVPMPE-V-QEKFQEQ--KA-4424
RYR1AVHEAGPGGADGAVAVTDGGPFRPEGAGGL>G<DMGDTTPAEPPTPEGSP-ILKRKLGVDGVE4484
RYR3IMSD-----LFGLHPKKEGS-LKHGPEVGL>G<DLSEIIGKDEPPTLESTVQKKRKA---QA-4327
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A4400Sc.13198G>T Putative BenignSIFT:
Polyphen: