Paralogue Annotation for RYR2 residue 4406

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4406
Reference Amino Acid: M - Methionine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4406

No paralogue variants have been mapped to residue 4406 for RYR2.



RYR2---IFGLDLKREGGQYKLIPHNPNAGLSDL>M<SN-PVPMPE-V-QEKFQEQ--KA---KEEE4428
RYR1PGGADGAVAVTDGGPFRPEGAGGLGDMGDT>T<PAEPPTPEGSP-ILKRKLGVDGVEEELPPE4490
RYR3---LFGLHPKKEGS-LKHGPEVGLGDLSEI>I<GKDEPPTLESTVQKKRKA---QA---AEMK4331
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.M4406Kc.13217T>A Putative BenignSIFT:
Polyphen: