Paralogue Annotation for RYR2 residue 461

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 461
Reference Amino Acid: G - Glycine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 461

No paralogue variants have been mapped to residue 461 for RYR2.

RYR2	ALSKKAKA----STVDLPIESVSLSLQDLI>G<YFHPPDEHLEHEDKQNRLRALKNRQNLFQE	491
RYR1	SFSGKPRGSGPPAGTALPIEGVILSLQDLI>I<YFEPPSEDLQHEEKQSKLRSLRNRQSLFQE	479
RYR3	----NRTA----APITLPIEEVLQTLQDLI>A<YFQPPEEEMRHEDKQNKLRSLKNRQNLFKE	478
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G461C	c.1381G>T	Putative Benign			SIFT: Polyphen: