Paralogue Annotation for RYR2 residue 4659

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4659
Reference Amino Acid: E - Glutamate
Protein Domain: Transmembrane region

Paralogue Variants mapped to RYR2 residue 4659

No paralogue variants have been mapped to residue 4659 for RYR2.

RYR2	QWDRLVINTQSFPNNYWDKFVKRKVMDKYG>E<FYGRDRISELLGMDKAALDFSDAREKKKPK	4689
RYR1	QWDRLVLNTPSFPSNYWDKFVKRKVLDKHG>D<IYGRERIAELLGMDLATLEITAHNER-KPN	4760
RYR3	QWDRLVINTPSFPNNYWDKFVKRKVINKYG>D<LYGAERIAELLGLDKNALDFSPVEET-KA-	4592
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E4659G	c.13976A>G	Putative Benign			SIFT: Polyphen: