Paralogue Annotation for RYR2 residue 559

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 559
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 559

No paralogue variants have been mapped to residue 559 for RYR2.

RYR2	ILNSLYELLAALIRGNRKNCAQFSGSLDWL>I<SRLERLEASSGILEVLHCVLVESPEALNII	589
RYR1	IVNLLYELLASLIRGNRSNCALFSTNLDWL>V<SKLDRLEASSGILEVLYCVLIESPEVLNII	577
RYR3	ILNLLYKLLAALIRGNRNNCAQFSNNLDWL>I<SKLDRLESSSGILEVLHCILTESPEALNLI	576
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I559V	c.1675A>G	Putative Benign			SIFT: Polyphen: