Paralogue Annotation for RYR2 residue 615

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 615
Reference Amino Acid: C - Cysteine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 615

No paralogue variants have been mapped to residue 615 for RYR2.

RYR2	ALNIIKEGHIKSIISLLDKHGRNHKVLDVL>C<SLCVCHGVAVRSNQHLICDNLLPGRDLLLQ	645
RYR1	VLNIIQENHIKSIISLLDKHGRNHKVLDVL>C<SLCVCNGVAVRSNQDLITENLLPGRELLLQ	633
RYR3	ALNLIAEGHIKSIISLLDKHGRNHKVLDIL>C<SLCLCNGVAVRANQNLICDNLLPRRNLLLQ	632
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.C615Y	c.1844G>A	Putative Benign			SIFT: Polyphen: