Paralogue Annotation for RYR2 residue 646

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 646
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 646

No paralogue variants have been mapped to residue 646 for RYR2.

RYR2	SLCVCHGVAVRSNQHLICDNLLPGRDLLLQ>T<RLVNHVSSMRPNIFLGVSEGSAQYKKWYYE	676
RYR1	SLCVCNGVAVRSNQDLITENLLPGRELLLQ>T<NLINYVTSIRPNIFVGRAEGTTQYSKWYFE	664
RYR3	SLCLCNGVAVRANQNLICDNLLPRRNLLLQ>T<RLINDVTSIRPNIFLGVAEGSAQYKKWYFE	663
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T646I	c.1937C>T	Putative Benign			SIFT: Polyphen: