Paralogue Annotation for RYR2 residue 651

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 651
Reference Amino Acid: H - Histidine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 651

No paralogue variants have been mapped to residue 651 for RYR2.

RYR2	HGVAVRSNQHLICDNLLPGRDLLLQTRLVN>H<VSSMRPNIFLGVSEGSAQYKKWYYELMVDH	681
RYR1	NGVAVRSNQDLITENLLPGRELLLQTNLIN>Y<VTSIRPNIFVGRAEGTTQYSKWYFEVMVDE	669
RYR3	NGVAVRANQNLICDNLLPRRNLLLQTRLIN>D<VTSIRPNIFLGVAEGSAQYKKWYFELIIDQ	668
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.H651Y	c.1951C>T	Putative Benign			SIFT: Polyphen: