Paralogue Annotation for RYR2 residue 708

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 708
Reference Amino Acid: G - Glycine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 708

No paralogue variants have been mapped to residue 708 for RYR2.

RYR2	MVDHTEPFVTAEATHLRVGWASTEGYSPYP>G<GGEEWGGNGVGDDLFSYGFDGLHLWSGCIA	738
RYR1	MVDEVTPFLTAQATHLRVGWALTEGYTPYP>G<AGEGWGGNGVGDDLYSYGFDGLHLWTGHVA	726
RYR3	IIDQVDPFLTAEPTHLRVGWASSSGYAPYP>G<GGEGWGGNGVGDDLYSYGFDGLHLWSGRIP	725
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G708A	c.2123G>C	Putative Benign		rs367988928	SIFT: tolerated Polyphen: possibly damaging