Paralogue Annotation for RYR2 residue 721

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 721
Reference Amino Acid: D - Aspartate
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 721

No paralogue variants have been mapped to residue 721 for RYR2.

RYR2	THLRVGWASTEGYSPYPGGGEEWGGNGVGD>D<LFSYGFDGLHLWSGCIARTVSSPNQHLLRT	751
RYR1	THLRVGWALTEGYTPYPGAGEGWGGNGVGD>D<LYSYGFDGLHLWTGHVARPVTSPGQHLLAP	739
RYR3	THLRVGWASSSGYAPYPGGGEGWGGNGVGD>D<LYSYGFDGLHLWSGRIPRAVASINQHLLRS	738
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D721E	c.2163T>A	Putative Benign			SIFT: Polyphen: