Paralogue Annotation for RYR2 residue 725

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 725
Reference Amino Acid: Y - Tyrosine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 725

No paralogue variants have been mapped to residue 725 for RYR2.

RYR2	VGWASTEGYSPYPGGGEEWGGNGVGDDLFS>Y<GFDGLHLWSGCIARTVSSPNQHLLRTDDVI	755
RYR1	VGWALTEGYTPYPGAGEGWGGNGVGDDLYS>Y<GFDGLHLWTGHVARPVTSPGQHLLAPEDVI	743
RYR3	VGWASSSGYAPYPGGGEGWGGNGVGDDLYS>Y<GFDGLHLWSGRIPRAVASINQHLLRSDDVV	742
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.Y725C	c.2174A>G	Putative Benign			SIFT: Polyphen: