Paralogue Annotation for RYR2 residue 741

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 741
Reference Amino Acid: V - Valine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 741

No paralogue variants have been mapped to residue 741 for RYR2.

RYR2	EEWGGNGVGDDLFSYGFDGLHLWSGCIART>V<SSPNQHLLRTDDVISCCLDLSAPSISFRIN	771
RYR1	EGWGGNGVGDDLYSYGFDGLHLWTGHVARP>V<TSPGQHLLAPEDVISCCLDLSVPSISFRIN	759
RYR3	EGWGGNGVGDDLYSYGFDGLHLWSGRIPRA>V<ASINQHLLRSDDVVSCCLDLGVPSISFRIN	758
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.V741L	c.2221G>T	Putative Benign			SIFT: Polyphen:
p.V741A	c.2222T>C	Putative Benign			SIFT: Polyphen: