Paralogue Annotation for RYR2 residue 774

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 774
Reference Amino Acid: P - Proline
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 774

No paralogue variants have been mapped to residue 774 for RYR2.

RYR2	PNQHLLRTDDVISCCLDLSAPSISFRINGQ>P<VQGMFENFNIDGLFFPVVSFSAGIKVRFLL	804
RYR1	PGQHLLAPEDVISCCLDLSVPSISFRINGC>P<VQGVFESFNLDGLFFPVVSFSAGVKVRFLL	792
RYR3	INQHLLRSDDVVSCCLDLGVPSISFRINGQ>P<VQGMFENFNTDGLFFPVMSFSAGVKVRFLM	791
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P774T	c.2320C>A	Putative Benign			SIFT: Polyphen: