Paralogue Annotation for RYR2 residue 837

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 837
Reference Amino Acid: S - Serine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 837

No paralogue variants have been mapped to residue 837 for RYR2.

RYR2	RHGEFKFLPPPGYAPCYEAVLPKEKLKVEH>S<REYKQERTYTRDLLGPTVSLTQAAFTPIPV	867
RYR1	RHGEFKFLPPPGYAPCHEAVLPRERLHLEP>I<KEYRREGPRGPHLVGPSRCLSHTDFVPCPV	855
RYR3	RHGEFKFLPPSGYAPCYEALLPKEKMRLEP>V<KEYKRDADGIRDLLGTTQFLSQASFIPCPV	854
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.S837T	c.2510G>C	Putative Benign		rs375607964	SIFT: deleterious Polyphen: benign