Paralogue Annotation for RYR2 residue 881

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 881
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 881

No paralogue variants have been mapped to residue 881 for RYR2.

RYR2	LGPTVSLTQAAFTPIPVDTSQIVLPPHLER>I<REKLAENIHELWVMNKIELGWQYGPVRDDN	911
RYR1	VGPSRCLSHTDFVPCPVDTVQIVLPPHLER>I<REKLAENIHELWALTRIEQGWTYGPVRDDN	899
RYR3	LGTTQFLSQASFIPCPVDTSQVILPPHLEK>I<RDRLAENIHELWGMNKIELGWTFGKIRDDN	898
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.I881V	c.2641A>G	Putative Benign			SIFT: Polyphen:
p.I881R	c.2642T>G	Putative Benign			SIFT: Polyphen:
p.I881K	c.2642T>A	Putative Benign			SIFT: Polyphen: