Paralogue Annotation for RYR2 residue 887

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 887
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 887

No paralogue variants have been mapped to residue 887 for RYR2.

RYR2	LTQAAFTPIPVDTSQIVLPPHLERIREKLA>E<NIHELWVMNKIELGWQYGPVRDDNKRQHPC	917
RYR1	LSHTDFVPCPVDTVQIVLPPHLERIREKLA>E<NIHELWALTRIEQGWTYGPVRDDNKRLHPC	905
RYR3	LSQASFIPCPVDTSQVILPPHLEKIRDRLA>E<NIHELWGMNKIELGWTFGKIRDDNKRQHPC	904
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E887K	c.2659G>A	Putative Benign		rs180862949	SIFT: deleterious Polyphen: probably damaging