Paralogue Annotation for RYR2 residue 921

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 921
Reference Amino Acid: F - Phenylalanine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 921

No paralogue variants have been mapped to residue 921 for RYR2.

RYR2	ELWVMNKIELGWQYGPVRDDNKRQHPCLVE>F<SKLPEQERNYNLQMSLETLKTLLALGCHVG	951
RYR1	ELWALTRIEQGWTYGPVRDDNKRLHPCLVD>F<HSLPEPERNYNLQMSGETLKTLLALGCHVG	939
RYR3	ELWGMNKIELGWTFGKIRDDNKRQHPCLVE>F<SKLPETEKNYNLQMSTETLKTLLALGCHIA	938
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.F921I	c.2761T>A	Putative Benign		rs372752031	SIFT: deleterious Polyphen: probably damaging