Paralogue Annotation for RYR2 residue 981

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 981
Reference Amino Acid: M - Methionine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 981

No paralogue variants have been mapped to residue 981 for RYR2.

RYR2	GISDEHAEDKVKKMKLPKNYQLTSGYKPAP>M<DLSFIKLTPSQEAMVDKLAENAHNVWARDR	1011
RYR1	GMADEKAEDNLKKTKLPKTYMMSNGYKPAP>L<DLSHVRLTPAQTTLVDRLAENGHNVWARDR	999
RYR3	AHVNPAAEEDLKKVKLPKNYMMSNGYKPAP>L<DLSDVKLLPPQEILVDKLAENAHNVWAKDR	998
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.M981V	c.2941A>G	Putative Benign			SIFT: Polyphen: