Paralogue Annotation for KCNH2 residue 1083

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 1083
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 1083

No paralogue variants have been mapped to residue 1083 for KCNH2.



KCNH2-------------LLQRQMTLVPPAYSAVT>T<P------------------------GPGPT1089
KCNH1-------------LDNVGEARSPQDRSPIL>A<EVKHSF-------------YPIPEQTLQAT925
KCNH3-------------MREGLQSLRQAVQLVLA>P<HREGP-------------CPRAS-----GE924
KCNH4-------------LSRELRHIMGLLQARLG>P<P------------------GHPAGSAWTPD926
KCNH5-------------LDKAGEARSPLEHSPIQ>A<DAKHPF-------------YPIPEQALQTT909
KCNH6-------------KHRNSSPRMP--HLAVA>T<D------------------------KTLAP931
KCNH7-------------LLQKQTTVVPPAYSMVT>A<GSEYQR-------------PIIQLMRTSQP1093
KCNH8-------------LGKDMRNVIQLLENVLS>P<QQPSRFCSLHSTSVCPSRESLQTRTSWSAH931
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1------------------------------>-<------------------------LGRPEG1210
CNGB3------------------------------>-<------------------------VRR---772
HCN1VSTLISRPHPTVG----ESLASIPQPVTAV>P<GTGLQ-----------------AG----G-831
HCN2APGPAASTRPAS------------------>-<----------------------------S-843
HCN3ATGDGSPGRKGS------------------>-<----------------------------G-735
HCN4GAQTLRRASPHSSGESMAAFPLFPRAGGGS>G<GSGS------------------------S-1132
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1083Ac.3247A>G Putative BenignSIFT:
Polyphen: