No paralogue variants have been mapped to residue 1102 for KCNH2.
| KCNH2 | -------GPGPTSTSPLL-----PVSPLP->T<LTLDSLSQVSQFMACEELPPGAPELPQ--- | 1129 |
| KCNH1 | -YPIPEQTLQATVLEVRH-----ELKEDIK>A<LNAKMTNIEKQLSEILRILTSRRS------ | 963 |
| KCNH3 | CPRAS-----GEGPCPASTSGLLQPLCVDT>G<ASSYCLQPPAGSVLSGTWPHPRPGPPPL-- | 971 |
| KCNH4 | -GHPAGSAWTPDPPCPQL-----RP----->P<CLSPCASRPPPSLQDTTLAEVH-CPASV-- | 962 |
| KCNH5 | -YPIPEQALQTTLQEVKH-----ELKEDIQ>L<LSCRMTALEKQVAEILKILSEKSVPQ---- | 949 |
| KCNH6 | -------KTLAPSSEQEQ-----PEGLWP->P<LASPLHPLEVQGLICG-------------- | 960 |
| KCNH7 | -PIIQLMRTSQPEASIKT-----DRSFSPS>S<QCPEFLDLEKSKLKSKESLSSGVHLNTA-- | 1135 |
| KCNH8 | ESLQTRTSWSAHQPCLHL-----QTGGAAY>T<QAQLCSSNITSDIWSVDPSSVGSSPQRT-- | 973 |
| CNGA1 | ------------------------------>-<------------------------------ | |
| CNGA2 | ------------------------------>-<------------------------------ | |
| CNGA3 | ------------------------------>-<------------------------------ | |
| CNGA4 | ------------------------------>-<------------------------------ | |
| CNGB1 | ------LGRPEGEEEGPA-----EPEEHSV>R<IC---------------------------- | 1226 |
| CNGB3 | ------VRR----TVLPR-----GTSRQSL>I<IS---------------------------- | 787 |
| HCN1 | ----AG----G---RST------------->-<VP-QRVTLFRQMSSGAIP------PNRGVP | 857 |
| HCN2 | ----------S---ST-------------P>R<LG-P-----------------TP-AARAAA | 858 |
| HCN3 | ----------G---SE-------------R>-<LP-PSGLL-------AKP------PRTAQP | 754 |
| HCN4 | ----------S---GGLG-----PPGRPYG>A<IPGQHVTLPRKTSSGSLPPPLSLFGARATS | 1174 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.T1102P | c.3304A>C | Putative Benign | SIFT: Polyphen: benign | ||
| p.Thr1102Ile | c.3305C>T | Unknown | SIFT: Polyphen: |