Paralogue Annotation for KCNH2 residue 112

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 112
Reference Amino Acid: V - Valine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 112

No paralogue variants have been mapped to residue 112 for KCNH2.



KCNH2DGS--------------------CFLCLVD>V<V-----------------------------113
KCNH1NRT--------------------PVWFFVK>I<A-----------------------------114
KCNH3SGL--------------------PFWCLLD>V<I-----------------------------114
KCNH4DGS--------------------AFWCLLD>M<M-----------------------------114
KCNH5NRT--------------------PVWFYMQ>I<A-----------------------------112
KCNH6DAS--------------------SFRCLVD>V<V-----------------------------113
KCNH7NGS--------------------TFICNTH>I<I-----------------------------113
KCNH8NGS--------------------PFWCLLD>I<V-----------------------------114
CNGA1GSF--------------------SYKSLRK>G<-G----------------------------75
CNGA2ADV--------------------D-APQQG>R<SG----------------------------65
CNGA3ADS--------------------GQGSFTG>Q<-G----------------------------69
CNGA4------------------------------>-<------------------------------
CNGB1KSSEVWRDEPAVATGAASDPAPPGRPQEMG>P<KLQARETPSLPTPIPLQPKEEPKEAPAPEP235
CNGB3------------------------------>-<------------------------------
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V112Mc.334G>A Putative BenignSIFT:
Polyphen: