No paralogue variants have been mapped to residue 133 for KCNH2.
| KCNH2 | --------PVK---NEDGAVIMFILNFEVV>M<EKDM-VG----------------------- | 139 |
| KCNH1 | --------PIR---NEQDKVVLFLCTFSDI>T<AFKQ-PI----------------------- | 140 |
| KCNH3 | --------PIK---NEKGEVALFLVSHKDI>S<ETK-NRG----------------------- | 140 |
| KCNH4 | --------PIK---NEMGEVVLFLFSFKDI>T<QSGSPGL----------------------- | 141 |
| KCNH5 | --------PIR---NEHEKVVLFLCTFKDI>T<LFKQ-PI----------------------- | 138 |
| KCNH6 | --------PVK---NEDGAVIMFILNFEDL>A<QL---------------------------- | 135 |
| KCNH7 | --------PVK---NQEGVAMMFIINFEYV>T<DNEN-AA----------------------- | 139 |
| KCNH8 | --------PIK---NEKGDVVLFLASFKDI>T<DTK-VKI----------------------- | 140 |
| CNGA1 | --------PSQREQYLPGAIALFNVNNSSN>K<DQ---------------------------- | 100 |
| CNGA2 | ---------FRRIVRLVGIIREWANKNFRE>E<EP---------------------------- | 89 |
| CNGA3 | ---------IARLSRLIFLLRRWAARHVHH>Q<DQ---------------------------- | 93 |
| CNGA4 | ------------------------------>-<DT---------------------------- | 5 |
| CNGB1 | LPQPVLHGKIG---EQEPDSPGICDVQTIS>I<LPGG---QVEPDLVLEEVEPPWEDAHQDVS | 321 |
| CNGB3 | ------------------------------>-<------------------------------ | |
| HCN1 | ----------------------------GG>G<GGGG-GGG---------------------- | 72 |
| HCN2 | ----------------------------GA>A<SGPA-PGP---------------------- | 138 |
| HCN3 | ----------------------------TA>A<SGPI-PKS---------------------- | 40 |
| HCN4 | ----------------------------QP>S<VDTA-IKV---------------------- | 190 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Met133Thr | c.398T>C | Unknown | SIFT: Polyphen: |