Paralogue Annotation for KCNH2 residue 147

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 147
Reference Amino Acid: H - Histidine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 147

No paralogue variants have been mapped to residue 147 for KCNH2.



KCNH2----------------------------TN>H<RGPPTSWLAPGRAKTFRLKLPALLALTARE177
KCNH1------------------------------>-<------------CKGWG-------------149
KCNH3------------------------------>-<------------WKETGGGRR---------153
KCNH4------------------------------>-<------------GRGDSNHEN---------154
KCNH5------------------------------>-<------------TKGWT-------------147
KCNH6------------------------------>-<-------LAKCSSRSLSQRLLSQSFLGSEG158
KCNH7-----------------------------N>-<---PILPIKTVNRKFFGFKFPGLRVLTYRK172
KCNH8------------------------------>-<---------------DKKEDK---------149
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1EDEEEEEEEEEEEEEEEVTEVLLDSCVVSQ>V<GVGQSEEDGTRPQSTSDQKLWEEVGEEAKK415
CNGB3PIGENNENEQS------------------->-<--SRRNEEGSHPSNQSQQ----TTAQEENK47
HCN1------------------------------>-<------------PAGG---F----------81
HCN2------------------------------>-<------------EAGSEEAG----------150
HCN3------------------------------>-<-------------------G----------41
HCN4------------------------------>-<-------------AAGDQIL----------201
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.H147Rc.440A>G Putative BenignSIFT:
Polyphen: