Paralogue Annotation for KCNH2 residue 224

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 224
Reference Amino Acid: G - Glycine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 224

No paralogue variants have been mapped to residue 224 for KCNH2.



KCNH2VVVDVDLTPAAPSSESLALDEVTAMDNHVA>G<LGPAEERRALVGPGS---------------239
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6------------------------------>-<--PG--------------------------169
KCNH7VVIDS----SKHSDDSVAMKHFKSPTKESC>S<PSEADDTKALIQPSK---------------224
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1EAEKEPQDWAETKEEPEAEAEAASSGVPAT>K<QHPEVQVEDTDADSCPLMAEENPPSTVLPP492
CNGB3EPHTNIQDKLSKKN---------SSGDLTT>N<PDPQNAAEPTGT------------------97
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Gly224Argc.670G>A UnknownSIFT:
Polyphen: