Paralogue Annotation for KCNH2 residue 232

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 232
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 232

No paralogue variants have been mapped to residue 232 for KCNH2.



KCNH2PAAPSSESLALDEVTAMDNHVAGLGPAEER>R<ALVGPGS-----------------P--PRS243
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6-------------------------PG--->-<------------------------------169
KCNH7-SKHSDDSVAMKHFKSPTKESCSPSEADDT>K<ALIQPSK-----------------CSPLVN230
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1WAETKEEPEAEAEAASSGVPATKQHPEVQV>E<DTDADSCPLMAEENPPSTVLPPPSPA---K497
CNGB3KLSKKN---------SSGDLTTNPDPQNAA>E<PTGT--------------------------97
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Arg232Leuc.695G>T UnknownSIFT:
Polyphen: