Paralogue Annotation for KCNH2 residue 240

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 240
Reference Amino Acid: P - Proline
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 240

No paralogue variants have been mapped to residue 240 for KCNH2.



KCNH2PAEERRALVGPGS----------------->P<--PRSA--PGQLPS--PRAHSLNPDASGSS264
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6PG---------------------------->-<------------------------------169
KCNH7EADDTKALIQPSK----------------->C<SPLVNISGPLDHSSPKRQWDRLYPDMLQSS255
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1PEVQVEDTDADSCPLMAEENPPSTVLPPPS>P<A---KS------------------DTLIVP504
CNGB3PQNAAEPTGT-------------------->-<----------------------------VP99
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Pro240Leuc.719C>T UnknownSIFT:
Polyphen: