Paralogue Annotation for KCNH2 residue 502

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 502
Reference Amino Acid: M - Methionine
Protein Domain: Transmembrane/Linker/Pore


Paralogue Variants mapped to KCNH2 residue 502

No paralogue variants have been mapped to residue 502 for KCNH2.



KCNH2TYVN-ANEEVVSHPGRIAVHYFKGW-FLID>M<VAAIPFDLLIFGSGSEE-------------519
KCNH1TFVG-PAGEVISDPKLIRMNYLKTW-FVID>L<LSCLPYDVINAFENVDEVSAFMGDPGKIGF330
KCNH3TFVS-KSGQVVFAPKSICLHYVTTW-FLLD>V<IAALPFDLLHAF-KVN--------------326
KCNH4TYVS-QSGQVISAPRSIGLHYLATW-FFID>L<IAALPFDLLYIF-NIT--------------328
KCNH5TFVG-PGGEVISDPKLIRMNYLKTW-FVID>L<LSCLPYDIINAFENVDEG------------315
KCNH6TYVN-TNDEVVSHPRRIAVHYFKGW-FLID>M<VAAIPFDLLIFRTGSDE-------------367
KCNH7TYVN-QNEEVVSDPAKIAIHYFKGW-FLID>M<VAAIPFDLLIFGSGSDE-------------518
KCNH8TYVS-KSGQVIFEARSICIHYVTTW-FIID>L<IAALPFDLLYAF-NVT--------------322
CNGA1GYLE--QGLLVKEELKLINKYKSNLQFKLD>V<LSLIPTDLLYFKLGWNY-------------267
CNGA2GFLE--QGLLVKDTKKLRDNYIHTLQFKLD>V<ASIIPTDLIYFAVDIHS-------------242
CNGA3GFLE--QGLMVSDTNRLWQHYKTTTQFKLD>V<LSLVPTDLAYLKVGTNY-------------270
CNGA4GFLE--QGILVVDKGRISSRYVRTWSFFLD>L<ASLMPTDVVYVRLGPHT-------------136
CNGB1QFVR--GGDIITDKKDMRNNYLKSRRFKMD>L<LSLLPLDFLYLKVGVN--------------758
CNGB3QFVR--GGDIIVDSNELRKHYRTSTKFQLD>V<ASIIPFDICYLFFGFN--------------320
HCN1GTVNEDSSEIILDPKVIKMNYLKSW-FVVD>F<ISSIPVDYIFLIVEK--GMDSEVYKTARAL254
HCN2GIVIEDNTEIILDPEKIKKKYLRTW-FVVD>F<VSSIPVDYIFLIVEK--GIDSEVYKTARAL323
HCN3GIVVEEGAEILLAPRAIRTRYLRTW-FLVD>L<ISSIPVDYIFLVVELEPRLDAEVYKTARAL207
HCN4GIVVEDNTEIILDPQRIKMKYLKSW-FMVD>F<ISSIPVDYIFLIVET--RIDSEVYKTARAL374
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.M502Ic.1506G>T Putative BenignSIFT:
Polyphen: