Paralogue Annotation for KCNH2 residue 989

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 989
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus

Paralogue Variants mapped to KCNH2 residue 989

No paralogue variants have been mapped to residue 989 for KCNH2.

KCNH2	-------------------EKSSDTCNPLS>G<-AFSGVSNIFS-------------------	999
KCNH1	------------------ECLGPKGGGGDC>A<K----RKSWAR-------------------	839
KCNH3	------------------LRLPPMPWNVPP>D<LSPRVVDGIED-------------------	830
KCNH4	------------------LLIPPLGTFGPP>D<LSPRIVDGIED-------------------	833
KCNH5	------------------ADQKCLKVNSPI>R<MKNGNGKGWLR-------------------	813
KCNH6	------------------LEQLQAQMNRLE>S<RVSSDLSRILQ-------------------	849
KCNH7	------------------IDKRSHSCKDIT>D<MRSWERENAHP-------------------	1002
KCNH8	------------------LQLSTLNNAGPP>D<LSPRIVDGIED-------------------	819
CNGA1	------------------------------>-<------------------------------
CNGA2	------------------------------>-<------------------------------
CNGA3	------------------------------>-<------------------------------
CNGA4	------------------------------>-<--E---------------------------	563
CNGB1	------------------------------>-<------A-----------------------	1180
CNGB3	------------------------------>-<------N-----------------------	737
HCN1	--SPCSYTTAVCSPPVQSPLAARTFHYASP>T<ASQLSLMQ----------------------	731
HCN2	-RPPPGPAPAAASPG------------PPP>P<ASP---------------------------	780
HCN3	-RSAWRSAGSPASPL------------VPV>R<AGPWASTS----------------------	669
HCN4	ARSPQAAQPSPAPPGARGGLGLPEHFLPPP>P<SSRSPSSSPGQLGQPPGELSLGLATGPLST	993
cons	> <

See full Alignment of Paralogues

Known Variants in KCNH2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G989S	c.2965G>A	Putative Benign			SIFT: Polyphen: