Paralogue Annotation for KCNQ1 residue 10

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 10
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNQ1 residue 10

No paralogue variants have been mapped to residue 10 for KCNQ1.



KCNQ1--------------------------P-PR>A<ER-KRWGWGRL----PG-------------22
KCNQ2--------------------------M--->-<-----VQKSR----NGG-------------9
KCNQ3--------------------------M-GL>K<AR-RAAGAAG----GGG-------------16
KCNQ4--------------------------M--->-<---------AEA-PPRR-------------8
KCNQ5--------------------------A-AG>L<WV-KSGAAAAAA-GGGR-------------31
KCNA1--------------------------MTVM>S<GE---------N--V-D-------------10
KCNA10-------------------FSNGKILISE->S<TN---------H--E-T-------------61
KCNA2--------------------------MTVA>T<GD---------P--A-D-------------10
KCNA3-------------------GRELPPDMTVV>P<GD---------H--L-L-------------62
KCNA4AHYRQSSFPHCSDLMPSGSEEKILRELSEE>E<ED---------E--E-EEEEEEEEGRFYYS143
KCNA5-------------------ADSGVRPLPPL>P<DP---------G--V-R-------------76
KCNA6------------------------------>-<------------------------------
KCNA7---------------------------EP->-<-----------R--C-P-------------6
KCNB1------------------------------>-<PA---------G------------------4
KCNB2------------------------------>A<PP---------G------------------8
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3-------------------GASKQQPAPPP>Q<PPESPPPPPLPP--Q-Q-------------40
KCNC4-------------------SGNKPPS---->-<------------------------------21
KCND1------------------------------>R<AA---------A--V-G-------------18
KCND2------------------------------>R<AA---------A--I-G-------------18
KCND3------------------------------>R<AA---------A--I-G-------------18
KCNF1------------------------------>-<ER---------S------------------8
KCNG1------------------------------>-<GD---------NSDY-D-------------12
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<RD---------GGLHPR-------------13
KCNS1------------------------------>-<VR---------G------------------8
KCNS2------------------------------>-<LW---------D------------------8
KCNS3------------------------------>-<FF----------------------------7
KCNV1------------------------------>G<RA---------L------------------8
KCNV2--------------------------QASI>H<GW---------T--E-G-------------49
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Ala10Aspc.29C>A UnknownSIFT:
Polyphen: