No paralogue variants have been mapped to residue 143 for KCNQ1.
| KCNQ1 | LERPT-GWKCFVYHFAVFLIVLVCLIFSVL>S<TIEQYA------------------------ | 149 |
| KCNQ2 | LERPR-G-WAFIYHAYVFLLVFSCLVLSVF>S<TIKEYE------------------------ | 119 |
| KCNQ3 | LERPR-G-WALLYHALVFLIVLGCLILAVL>T<TFKEYE------------------------ | 149 |
| KCNQ4 | LERPR-G-WAFVYHVFIFLLVFSCLVLSVL>S<TIQEHQ------------------------ | 125 |
| KCNQ5 | LERPR-G-WAFIYHAFVFLLVFGCLILSVF>S<TIPEHT------------------------ | 153 |
| KCNA1 | FEYPESSGPARVIAIVSVMVILISIVIFCL>E<TLPELKDDK-DF--------TG-------- | 200 |
| KCNA10 | FEYPESSSAARAVAVVSVLVVVISITIFCL>E<TLPEFREDR-EL--------KV-------- | 249 |
| KCNA2 | FEYPESSGPARIIAIVSVMVILISIVSFCL>E<TLPIFRDEN-ED--------MHGSG---V- | 200 |
| KCNA3 | FEYPESSGPARGIAIVSVLVILISIVIFCL>E<TLPEFRDEK-DY--------PA-ST---SQ | 271 |
| KCNA4 | FEYPESSSPARGIAIVSVLVILISIVIFCL>E<TLPEFRDDR-DL--------VM-AL---SA | 344 |
| KCNA5 | FEYPESSGSARAIAIVSVLVILISIITFCL>E<TLPEFRDER-ELLRHPPAP---------HQ | 290 |
| KCNA6 | FEYPESSGPARGIAIVSVLVILISIVIFCL>E<TLPQFRVDG-RGGNNGGVSRVS-PVSRGSQ | 222 |
| KCNA7 | FEFPESSQAARVLAVVSVLVILVSIVVFCL>E<TLPDFRDDR-DGTGL-----AA-AA---AA | 183 |
| KCNB1 | LEKPNSSVAAKILAIISIMFIVLSTIALSL>N<TLPELQSLD-EF--------GQ-------- | 222 |
| KCNB2 | LEKPNSSVAAKILAIVSILFIVLSTIALSL>N<TLPELQETD-EF--------GQ-------- | 226 |
| KCNC1 | FEDPYSSRYARYVAFASLFFILVSITTFCL>E<THERFNPIV-NK--------TE-I----E- | 225 |
| KCNC2 | FEDPYSSRAARFIAFASLFFILVSITTFCL>E<THEAFNI---VK--------NK-T----E- | 262 |
| KCNC3 | FEDPYSSRAARYVAFASLFFILISITTFCL>E<THEGFIHIS-NK--------TV-T----QA | 326 |
| KCNC4 | FEDPYSSRAARVVAFASLFFILVSITTFCL>E<THEAFNI---DR-NV-----TE-I----L- | 261 |
| KCND1 | FENPHTSTAALVFYYVTGFFIAVSVIANVV>E<TIPCRGSAR-RS--------SR-------- | 219 |
| KCND2 | FENPHTSTMALVFYYVTGFFIAVSVIANVV>E<TVPCGS-SP-GH--------IK-------- | 217 |
| KCND3 | FENPHTSTLALVFYYVTGFFIAVSVITNVV>E<TVPCGT-VP-G---------SK-------- | 214 |
| KCNF1 | LEKPESSCPARVVAVLSFLLILVSSVVMCM>G<TIPELQVLD-AE--------GN-------- | 215 |
| KCNG1 | VERPHSGLPGKVFACLSVLFVTVTAVNLSV>S<TLPSLREEEE-Q--------GH-------- | 260 |
| KCNG2 | VDNPHSGLAGKLFACVSVSFVAVTAVGLCL>S<TMPDIRAEEE-R--------GE-------- | 210 |
| KCNG3 | FEEPTSSLAAQILASVSVVFVIVSMVVLCA>S<TLPDWRN-AAAD--------NR-------- | 204 |
| KCNG4 | VENPQSGLPGKVFACLSILFVATTAVSLCV>S<TMPDLRAEED-Q--------GE-------- | 254 |
| KCNS1 | MENPGYSLPSKLFSCVSISVVLASIAAMCI>H<SLPEYQARE-AA--------AA-------- | 253 |
| KCNS2 | LDNPGYSVLSRVFSILSILVVMGSIITMCL>N<SLPDFQIPD-SQ--------GN-------- | 220 |
| KCNS3 | MENPAYCLSAKLIAISSLSVVLASIVAMCV>H<SMSEFQNED-GE------------------ | 216 |
| KCNV1 | LEKPGSSTAARIFGVISIIFVVVSIINMAL>M<SAEL-----------------S-------- | 235 |
| KCNV2 | MEKPFSSVAAKAIGVASSTFVLVSVVALAL>N<TVEEMQQHS-GQ--------GE-------- | 293 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Ser143Phe | c.428C>T | Unknown | SIFT: Polyphen: |