No paralogue variants have been mapped to residue 196 for KCNQ1.
| KCNQ1 | FFGTEYVVRLWSAGCRSKYVGLWGRLRFAR>K<PISIIDLIVVVASMVVLCVG---------- | 216 |
| KCNQ2 | VFGVEYFVRIWAAGCCCRYRGWRGRLKFAR>K<PFCVIDIMVLIASIAVLAAG---------- | 186 |
| KCNQ3 | IFGAEFALRIWAAGCCCRYKGWRGRLKFAR>K<PLCMLDIFVLIASVPVVAVG---------- | 216 |
| KCNQ4 | VFGLEYIVRVWSAGCCCRYRGWQGRFRFAR>K<PFCVIDFIVFVASVAVIAAG---------- | 192 |
| KCNQ5 | VFGLEFIIRIWSAGCCCRYRGWQGRLRFAR>K<PFCVIDTIVLIASIAVVSAK---------- | 220 |
| KCNA1 | WFSFELVVR---------FFACPSKTDFFK>N<IMNFIDIVAIIPYFITLGTEIAEQEG---- | 278 |
| KCNA10 | WFTFELVLR---------FVVCPSKTDFFR>N<IMNIIDIISIIPYFATLITELVQETEP--- | 329 |
| KCNA2 | WFSFEFLVR---------FFACPSKAGFFT>N<IMNIIDIVAIIPYFITLGTELAEKPE---- | 279 |
| KCNA3 | WFSFELLVR---------FFACPSKATFSR>N<IMNLIDIVAIIPYFITLGTELAERQ----- | 351 |
| KCNA4 | WFSFEFVVR---------CFACPSQALFFK>N<IMNIIDIVSILPYFITLGTDLAQQQGG--- | 429 |
| KCNA5 | WFTFELLVR---------FFACPSKAGFSR>N<IMNIIDVVAIFPYFITLGTELAEQQ---PG | 382 |
| KCNA6 | WFTFELLVR---------FSACPSKPAFFR>N<IMNIIDLVAIFPYFITLGTELVQQQEQQPA | 324 |
| KCNA7 | WFSFELLVR---------LLVCPSKAIFFK>N<VMNLIDFVAILPYFVALGTELARQR----- | 265 |
| KCNB1 | WFTMEYLLR---------FLSSPKKWKFFK>G<PLNAIDLLAILPYYVTIFLTES---N---- | 283 |
| KCNB2 | WFTMEYLLR---------FLSSPNKWKFFK>G<PLNVIDLLAILPYYVTIFLTES---N---- | 287 |
| KCNC1 | WFTFEFLMR---------VIFCPNKVEFIK>N<SLNIIDFVAILPFYLEVGLSG--------- | 297 |
| KCNC2 | WFTFEFLVR---------IVFSPNKLEFIK>N<LLNIIDFVAILPFYLEVGLSG--------- | 334 |
| KCNC3 | WFTFEFLMR---------ITFCPDKVEFLK>S<SLNIIDCVAILPFYLEVGLSG--------- | 400 |
| KCNC4 | WFTLEFLVR---------IVCCPDTLDFVK>N<LLNIIDFVAILPFYLEVGLSG--------- | 333 |
| KCND1 | IFTGEYLLR---------LFAAPSRCRFLR>S<VMSLIDVVAILPYYIGLLVP---------- | 282 |
| KCND2 | IFTVEYLLR---------LAAAPSRYRFVR>S<VMSIIDVVAILPYYIGLVMT---------- | 280 |
| KCND3 | IFTVEYLLR---------LFAAPSRYRFIR>S<VMSIIDVVAIMPYYIGLVMT---------- | 277 |
| KCNF1 | WFTLEYLLR---------LFSSPNKLHFAL>S<FMNIVDVLAILPFYVSLTLTHL-------- | 275 |
| KCNG1 | WFSLEFLLR---------LIQAPSKFAFLR>S<PLTLIDLVAILPYYITLLVDGAAAGRR--- | 326 |
| KCNG2 | WFSFEFLLR---------SLQAESKCAFLR>A<PLNIIDILALLPFYVSLLLGL-----A--- | 271 |
| KCNG3 | WFTAECIVR---------FIVSKNKCEFVK>R<PLNIIDLLAITPYYISVLMTV--------- | 273 |
| KCNG4 | WFSLEFCLR---------FVQAQDKCQFFQ>G<PLNIIDILAISPYYVSLAVSEEPPEDG--- | 320 |
| KCNS1 | WFSFEVSSR---------LLLAPSTRNFFC>H<PLNLIDIVSVLPFYLTLLAGVALG-D---- | 328 |
| KCNS2 | WFTFELVAR---------FAVAPDFLKFFK>N<ALNLIDLMSIVPFYITLVVNLV---V---- | 281 |
| KCNS3 | WFTGELAVR---------LAAAPCQKKFWK>N<PLNIIDFVSIIPFYATLAVDTK---E---- | 276 |
| KCNV1 | WFTGEFVLR---------FLCVRDRCRFLR>K<VPNIIDLLAILPFYITLLVESLSG-S---- | 298 |
| KCNV2 | FFTLEYLLR---------LASTPDLRRFAR>S<ALNLVDLVAILPLYLQLLLECFTGEGH--- | 360 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Lys196Thr | c.587A>C | Unknown | SIFT: Polyphen: |