Paralogue Annotation for KCNQ1 residue 28

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 28
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNQ1 residue 28

No paralogue variants have been mapped to residue 28 for KCNQ1.



KCNQ1-S---------------------------->A<---G------------------LAKKCPFS37
KCNQ2GFVGLD-----PGA---------------P>D<----------------------STRDGALL41
KCNQ3EQVTLA-----------------------L>G<--AG------------------ADKDGTLL68
KCNQ4E-LVAL-----------------------T>A<---V------------------QSEQGEAG37
KCNQ5R-VLLN-----------------------S>A<---A------------------ARGDGLLL60
KCNA1ERVVINI----------------------->-<------------------SG--LRFETQLK53
KCNA10QRVIINI----------------------->-<------------------AG--LRFETQLR102
KCNA2ERVVINI----------------------->-<------------------SG--LRFETQLK49
KCNA3ERVVINI----------------------->-<------------------SG--LRFETQLK120
KCNA4ERVVINV----------------------->-<------------------SG--LRFETQMK192
KCNA5QRVHINI----------------------->-<------------------SG--LRFETQLG136
KCNA6ERLVINI----------------------->-<------------------SG--LRFETQLR57
KCNA7ERLVLNV----------------------->-<------------------AG--LRFETRAR29
KCNB1RRVRLNV----------------------->-<------------------GG--LAHEVLWR47
KCNB2RRVKINV----------------------->-<------------------GG--LNHEVLWR51
KCNC1ERIVINVGGTRHQTYRSTLRTLPGTRLAWL>A<EPDAH-------------------------43
KCNC2ERVILNVGGTRHETYRSTLKTLPGTRLALL>A<SSEPPGDCLTTAGDKLQPSPPPLSPPPRAP68
KCNC3GKIVINVGGVRHETYRSTLRTLPGTRLAGL>T<EPEAA-------------------------123
KCNC4EKIIINVGGTRHETYRSTLRTLPGTRLAWL>A<DPDGG-------------------------71
KCND1EVLVVNV----------------------->-<------------------SG--RRFETWKN56
KCND2ALIVLNV----------------------->-<------------------SG--TRFQTWQD57
KCND3ELIVLNV----------------------->-<------------------SG--RRFQTWRT56
KCNF1IEIVVNV----------------------->-<------------------GG--VRQVLYGD39
KCNG1RRIIINV----------------------->-<------------------GG--IKYSLPWT79
KCNG2RHVIINV----------------------->-<------------------GG--CRVRLAWA33
KCNG3ASVVLNV----------------------->-<------------------GG--ARYSLSRE25
KCNG4KEILINV----------------------->-<------------------GG--RRYLLPWS75
KCNS1EALRVNV----------------------->-<------------------GG--VRRQLSAR66
KCNS2GEIRINV----------------------->-<------------------GG--FKRRLRSH33
KCNS3ELVNLNV----------------------->-<------------------GG--FKQSVDQS31
KCNV1DCFTVNV----------------------->-<------------------GG--SRFVLSQQ55
KCNV2STLNVNV----------------------->-<------------------GG--HSYQLDYC113
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A28Vc.83C>T Putative BenignSIFT:
Polyphen: