Paralogue Annotation for KCNQ1 residue 416

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 416
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 416

No paralogue variants have been mapped to residue 416 for KCNQ1.



KCNQ1------------------TLLSPSPKPKKS>V<VVKKKKFKLDKDNGV---------------431
KCNQ2PE-PSP-SKG--SP-CRGPLCGCCPGRSSQ>K<VSLKDRV-FSSPRGV---------------450
KCNQ3--------------------KEQLEAASSQ>K<LGLLDRVRLSNPRGS---------------438
KCNQ4PD-GAP-SRYPPVATCHRPGSTSFCPGESS>R<MGIKDRIRMGSSQRR---------------448
KCNQ5------------LHTCSPTKKEQGEASSSQ>K<LSFKERVRMASPRGQ---------------433
KCNA1AHYRQV-NIR-------------------->-<------------------------------474
KCNA10--G--------------------------->-<------------------------------502
KCNA2--FREE-NLK-------------------->-<------------------------------478
KCNA3TPFKTG-N-S-------------------->-<------------------------------552
KCNA4CAKEEKCQGK-------------------->-<------------------------------632
KCNA5KSNVD------------------------->-<------------------------------595
KCNA6PSYLPT------------------------>-<------------------------------515
KCNA7---LPP-P---------------------->-<------------------------------443
KCNB1DNHLSPNKWKW------------------->-<---TKRTLSETSSSK---------------502
KCNB2DNHLSPSRWKW------------------->-<---ARKALSETSSNK---------------506
KCNC1VAKAALANED-------------------->-<------------------------------518
KCNC2----VLSGDD-------------------->-<------------------------------544
KCNC3PAAAALAHED-------------------->-<------------------------------676
KCNC4-ANAVLSDEE-------------------->-<------------------------------554
KCND1HHHLLHCLEKT------------------->-<--------------T---------------489
KCND2HHHLLHCLEKT------------------->-<--------------T---------------489
KCND3HHHLLHCLEKT------------------->-<--------------TGLSYLVDDPLLSVRT502
KCNF1RLKLSHSDTF-------------------->-<---------IPLLTE---------------482
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1QM---------------------------->-<------------------------------525
KCNS2DSL--------------------------->-<------------------------------476
KCNS3ASSIEDNEDI-------------------->-<---------CNTTSL---------------485
KCNV1DDF--------------------------->-<---------W--------------------499
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V416Mc.1246G>A Putative BenignSIFT:
Polyphen: