Paralogue Annotation for KCNQ1 residue 418

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 418
Reference Amino Acid: V - Valine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 418

No paralogue variants have been mapped to residue 418 for KCNQ1.



KCNQ1----------------TLLSPSPKPKKSVV>V<KKKKFKLDKDNGV-----------------431
KCNQ2-PSP-SKG--SP-CRGPLCGCCPGRSSQKV>S<LKDRV-FSSPRGV-----------------450
KCNQ3------------------KEQLEAASSQKL>G<LLDRVRLSNPRGS-----------------438
KCNQ4-GAP-SRYPPVATCHRPGSTSFCPGESSRM>G<IKDRIRMGSSQRR-----------------448
KCNQ5----------LHTCSPTKKEQGEASSSQKL>S<FKERVRMASPRGQ-----------------433
KCNA1YRQV-NIR---------------------->-<------------------------------474
KCNA10G----------------------------->-<------------------------------502
KCNA2FREE-NLK---------------------->-<------------------------------478
KCNA3FKTG-N-S---------------------->-<------------------------------552
KCNA4KEEKCQGK---------------------->-<------------------------------632
KCNA5NVD--------------------------->-<------------------------------595
KCNA6YLPT-------------------------->-<------------------------------515
KCNA7-LPP-P------------------------>-<------------------------------443
KCNB1HLSPNKWKW--------------------->-<-TKRTLSETSSSK-----------------502
KCNB2HLSPSRWKW--------------------->-<-ARKALSETSSNK-----------------506
KCNC1KAALANED---------------------->-<------------------------------518
KCNC2--VLSGDD---------------------->-<------------------------------544
KCNC3AAALAHED---------------------->-<------------------------------676
KCNC4NAVLSDEE---------------------->-<------------------------------554
KCND1HLLHCLEKT--------------------->-<------------T-----------------489
KCND2HLLHCLEKT--------------------->-<------------T-----------------489
KCND3HLLHCLEKT--------------------->-<------------TGLSYLVDDPLLSVRTST504
KCNF1KLSHSDTF---------------------->-<-------IPLLTE-----------------482
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2L----------------------------->-<------------------------------476
KCNS3SIEDNEDI---------------------->-<-------CNTTSL-----------------485
KCNV1F----------------------------->-<-------W----------------------499
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V418Ic.1252G>A Putative BenignSIFT:
Polyphen: