Paralogue Annotation for KCNQ1 residue 432

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 432
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 432

No paralogue variants have been mapped to residue 432 for KCNQ1.



KCNQ1KKFKLDKDNGV------------------->T<P-GEKMLTVPHITCDPPEERRL--------453
KCNQ2DRV-FSSPRGV------------------->A<AKGKGSPQAQTVRRSPSADQSLED-SPSKV480
KCNQ3DRVRLSNPRGS------------------->N<TKGKL--------FTPLNVDAIEE-SPSKE460
KCNQ4DRIRMGSSQRR------------------->T<GPSKQHLAPPTMPTSPSSEQVGEATSPTKV479
KCNQ5ERVRMASPRGQ------------------->S<IKSRQ--ASVGDRRSPSTDITAEG-SPTKV461
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1KRTLSETSSSK------------------->S<FETKEQGSPEK-------ARSSSSPQH---523
KCNB2RKALSETSSNK------------------->S<FENKYQEVSQKDSHEQLNNTSSSSPQH---534
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1----------T------------------->C<HE-----------------F----------493
KCND2----------T------------------->N<HE-----------------F----------493
KCND3----------TGLSYLVDDPLLSVRTSTIK>N<HE-----------------F----------510
KCNF1-----IPLLTE------------------->-<------------------------------482
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3-----CNTTSL------------------->E<NCTA--------------------------490
KCNV1-----W------------------------>-<------------------------------499
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T432Ic.1295C>T Putative BenignSIFT:
Polyphen: