Paralogue Annotation for KCNQ1 residue 444

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 444
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 444

No paralogue variants have been mapped to residue 444 for KCNQ1.



KCNQ1-----------------TP-GEKMLTVPHI>T<CDPPEERRL--------DHFSVDGYDSSVR466
KCNQ2-----------------AAKGKGSPQAQTV>R<RSPSADQSLED-SPSKVPKSW--SFGDRSR491
KCNQ3-----------------NTKGKL------->-<FTPLNVDAIEE-SPSKEPKPV--GLNNKER471
KCNQ4-----------------TGPSKQHLAPPTM>P<TSPSSEQVGEATSPTKVQKSW--SFNDRTR490
KCNQ5-----------------SIKSRQ--ASVGD>R<RSPSTDITAEG-SPTKVQKSW--SFNDRTR472
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1-----------------SFETKEQGSPEK->-<-----ARSSSSPQH-----L----------524
KCNB2-----------------SFENKYQEVSQKD>S<HEQLNNTSSSSPQH-----L----------535
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1-----------------CHE---------->-<------F------------T----------494
KCND2-----------------NHE---------->-<------F------------V----------494
KCND3SYLVDDPLLSVRTSTIKNHE---------->-<------F------------I----------511
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3-----------------ENCTA-------->-<------------------------------490
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T444Mc.1331C>T Putative BenignSIFT:
Polyphen:
p.T444Kc.1331C>A Putative BenignSIFT:
Polyphen: