Paralogue Annotation for KCNQ1 residue 482

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 482
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 482

No paralogue variants have been mapped to residue 482 for KCNQ1.



KCNQ1-------------------------PHFMR>T<N----------------SFAEDLDL-----491
KCNQ2-----------------------AASRQNS>E<E----------------ASLPGEDI-----517
KCNQ3------------------------YAFWQS>S<E----------------DAGTGDPM-----496
KCNQ4--------------------------PRTS>A<E----------------DA-PSEEV-----511
KCNQ5-----------------------QPKPVID>A<D----------------TALGTDDV-----499
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1KPKEELEMESIPSPVAPLP-TRTEGVIDMR>S<MSSIDSFISCATDFPEATRFSHSP---LTS611
KCNB2AYEEEIEMEEVVCPQEQLAVAQTEVIVDMK>S<TSSIDSFTSCATDFTETERSPLPPPSASHL629
KCNC1------------------------------>-<------------------CPHIDQA-----525
KCNC2------------------------------>-<------------------STGSEPP-----551
KCNC3------------------------------>-<------------------CPAIDQP-----683
KCNC4------------------------------>-<------------------GAGLTQP-----561
KCND1-----------------------TFSEALG>A<V----------------SPGGRT-S-----513
KCND2-----------------------VFEESCM>E<V----------------ATVNRPSS-----514
KCND3-----------------------MFEQNCM>E<S----------------SMQNYPST-----531
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T482Nc.1445C>A Putative BenignSIFT:
Polyphen: