Paralogue Annotation for KCNQ1 residue 499

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 499
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 499

No paralogue variants have been mapped to residue 499 for KCNQ1.



KCNQ1-------EGET----------------LLT>P<ITHISQLREHHRATIKV-------------516
KCNQ2-------VDDK----------------SCP>C<EFVTEDLTPGLKVSIRA-------------542
KCNQ3-------AEDR----------------GYG>N<DFPIEDMIPTLKAAIRA-------------521
KCNQ4-------AEEK----------------SYQ>C<ELTVDDIMPAVKTVIRS-------------536
KCNQ5-------YDEK----------------GCQ>C<DVSVEDLTPPLKTVIRA-------------524
KCNA1-----------------------------T>A<N----CTTAN--QNCVN-------------487
KCNA10------------------------------>-<----------------G-------------503
KCNA2-----------------------------T>A<N----CTLAN--TNYVN-------------491
KCNA3-----------------------------T>A<T----CTTNNNPNSCVN-------------567
KCNA4-----------------------------G>D<D----SETDK--NNCSN-------------645
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------P-----HRAYA-------------521
KCNA7------------------------------>-<------------LWAPP-------------448
KCNB1--RF--VEAN-------PSPDASQHSSFFI>E<SPKSSMKTNNPLKLRAL-------------672
KCNB2EYAPVDITVNLDASGSQCGLHSPLQSDNAT>D<SPKSSLKGSNPLKSRSL-------------715
KCNC1---------------------------LTP>D<EGLPFTRSGTRERY--G-------------544
KCNC2---------------------------LSP>P<ERLPIRRSSTRDKNRRG-------------572
KCNC3-------A-------------------MSP>E<DKSPIT-PGSRGRYSRD-------------704
KCNC4-------LASS----------------PTP>E<ERRALRRSTTRDRNKKA-------------586
KCND1-------RSTS----------------VSS>Q<PVGPGSLLSSCCPRRAKRRAIRLANSTASV551
KCND2-------HSPS----------------LSS>Q<Q----GVTSTCCSRRHKK-TFRIPNANVSG547
KCND3-------RSPS----------------LSS>H<P----GLTTTCCSRRSKK-TTHLPNSNLPA564
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P499Sc.1495C>T Putative BenignSIFT:
Polyphen: