Paralogue Annotation for KCNQ1 residue 501

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 501
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 501

No paralogue variants have been mapped to residue 501 for KCNQ1.



KCNQ1-----EGET----------------LLTPI>T<HISQLREHHRATIKV---------------516
KCNQ2-----VDDK----------------SCPCE>F<VTEDLTPGLKVSIRA---------------542
KCNQ3-----AEDR----------------GYGND>F<PIEDMIPTLKAAIRA---------------521
KCNQ4-----AEEK----------------SYQCE>L<TVDDIMPAVKTVIRS---------------536
KCNQ5-----YDEK----------------GCQCD>V<SVEDLTPPLKTVIRA---------------524
KCNA1---------------------------TAN>-<---CTTAN--QNCVN---------------487
KCNA10------------------------------>-<--------------G---------------503
KCNA2---------------------------TAN>-<---CTLAN--TNYVN---------------491
KCNA3---------------------------TAT>-<---CTTNNNPNSCVN---------------567
KCNA4---------------------------GDD>-<---SETDK--NNCSN---------------645
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<----P-----HRAYA---------------521
KCNA7------------------------------>-<----------LWAPP---------------448
KCNB1RF--VEAN-------PSPDASQHSSFFIES>P<KSSMKTNNPLKLRAL---------------672
KCNB2APVDITVNLDASGSQCGLHSPLQSDNATDS>P<KSSLKGSNPLKSRSL---------------715
KCNC1-------------------------LTPDE>G<LPFTRSGTRERY--G---------------544
KCNC2-------------------------LSPPE>R<LPIRRSSTRDKNRRG---------------572
KCNC3-----A-------------------MSPED>K<SPIT-PGSRGRYSRD---------------704
KCNC4-----LASS----------------PTPEE>R<RALRRSTTRDRNKKA---------------586
KCND1-----RSTS----------------VSSQP>V<GPGSLLSSCCPRRAKRRAIRLANSTASVS-552
KCND2-----HSPS----------------LSSQQ>-<---GVTSTCCSRRHKK-TFRIPNANVSGSH549
KCND3-----RSPS----------------LSSHP>-<---GLTTTCCSRRSKK-TTHLPNSNLPATR566
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T501Ac.1501A>G Putative BenignSIFT:
Polyphen: