No paralogue variants have been mapped to residue 51 for KCNQ1.
| KCNQ1 | -P---------------------A--GGAL>Y<APIAPGAPGP--------APPASPAAPAAP | 73 |
| KCNQ2 | -E---------------------------->-<----A-PK---------------RGSILS- | 55 |
| KCNQ3 | -R---------------------------->-<--------DEG-----QR---R----TPQ- | 83 |
| KCNQ4 | -P---------------------------->-<--RRLGLLGSP-----L------PPGAPLP | 59 |
| KCNQ5 | -A---------------------------->-<--ATLGGGGGG-----LRESRRGKQGARMS | 88 |
| KCNA1 | -------------KR-M---RYFDPLRNEY>F<FDRNRPSFDAILYYYQSGGRLRRPVNVPLD | 111 |
| KCNA10 | -------------KR-M---QFFDSMRNEY>F<FDRNRPSFDGILYYYQSGGKIRRPANVPID | 160 |
| KCNA2 | -------------KR-M---RYFDPLRNEY>F<FDRNRPSFDAILYYYQSGGRLRRPVNVPLD | 107 |
| KCNA3 | -------------RR-M---RYFDPLRNEY>F<FDRNRPSFDAILYYYQSGGRIRRPVNVPID | 178 |
| KCNA4 | -------------KR-T---QYFDPLRNEY>F<FDRNRPSFDAILYYYQSGGRLKRPVNVPFD | 250 |
| KCNA5 | -------------KR-L---RYFDPLRNEY>F<FDRNRPSFDGILYYYQSGGRLRRPVNVSLD | 194 |
| KCNA6 | -------------RR-V---RFFDPLRNEY>F<FDRNRPSFDAILYYYQSGGRLRRPVNVPLD | 115 |
| KCNA7 | -------------RR-G---RFYDDARREY>F<FDRHRPSFDAVLYYYQSGGRLRRPAHVPLD | 87 |
| KCNB1 | -HD----------SL-LEVCDDYSLDDNEY>F<FDRHPGAFTSILNFYRT-GRLHMMEEMCAL | 113 |
| KCNB2 | -HE----------SL-LEVCDDYNLNENEY>F<FDRHPGAFTSILNFYRT-GKLHMMEEMCAL | 117 |
| KCNC1 | ----------------S--HFDYDPRADEF>F<FDRHPGVFAHILNYYRT-GKLHCPADVCGP | 85 |
| KCNC2 | -------------RGGR--ASDHPGGGREF>F<FDRHPGVFAYVLNYYRT-GKLHCPADVCGP | 132 |
| KCNC3 | ----------------A--RFDYDPGADEF>F<FDRHPGVFAYVLNYYRT-GKLHCPADVCGP | 165 |
| KCNC4 | ---------------GS--SGSSGGGGCEF>F<FDRHPGVFAYVLNYYRT-GKLHCPADVCGP | 124 |
| KCND1 | -------------KE-F----FYDADSGEY>F<FDRDPDMFRHVLNFYRT-GRLHCPRQECIQ | 112 |
| KCND2 | -------------RD-F----FYHPETQQY>F<FDRDPDIFRHILNFYRT-GKLHYPRHECIS | 113 |
| KCND3 | -------------KE-F----FFNEDTKEY>F<FDRDPEVFRCVLNFYRT-GKLHYPRYECIS | 112 |
| KCNF1 | GYD----------TI-FSLCDDYDPGKREF>Y<FDRDPDAFKCVIEVYYF-GEVHMKKGICPI | 107 |
| KCNG1 | -FD----------DI-LNVCDDYDVTCNEF>F<FDRNPGAFGTILTFLRA-GKLRLLREMCAL | 145 |
| KCNG2 | -HD----------DL-LRVCDDYDVSRDEF>F<FDRSPCAFRAIVALLRA-GKLRLLRGPCAL | 99 |
| KCNG3 | -ER----------DV-LEVCDDYDRERNEY>F<FDRHSEAFGFILLYVRGHGKLRFAPRMCEL | 92 |
| KCNG4 | -YE----------EI-VQLCDDYDEDSQEF>F<FDRSPSAFGVIVSFLAA-GKLVLLQEMCAL | 141 |
| KCNS1 | -EE----------QA-RRLCDDYDEAAREF>Y<FDRHPGFFLSLLHFYRT-GHLHVLDELCVF | 132 |
| KCNS2 | -RE----------AI-LELCDDYDDVQREF>Y<FDRNPELFPYVLHFYHT-GKLHVMAELCVF | 99 |
| KCNS3 | -EE----------AI-LELCDDYSVADKEY>Y<FDRNPSLFRYVLNFYYT-GKLHVMEELCVF | 97 |
| KCNV1 | -SYRRPGALAAVPSP-LELCDDANPVDNEY>F<FDRSSQAFRYVLHYYRT-GRLHVMEQLCAL | 131 |
| KCNV2 | -RS----------RQ-LSLCDDYEEQTDEY>F<FDRDPAVFQLVYNFYLS-GVLLVLDGLCPR | 179 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.Y51C | c.152A>G | Other Cardiac Phenotype | SIFT: Polyphen: | ||
| Reports | Other Cardiac Phenotype | Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths. Forensic Sci Int. 2014 237:90-9. doi: 10.1016/j.forsciint.2014.01.014. 24631775 | |||