No paralogue variants have been mapped to residue 579 for KCNQ1.
KCNQ1 | ----------V-----------------SE>K<SKDRGSNTIGARLNRVEDKVTQLDQRLALI | 609 |
KCNQ2 | -KDR--T--KG-----------------PA>E<AELPEDPSMMGRLGKVEKQVLSMEKKLDFL | 640 |
KCNQ3 | -KHKKSQKGSAFTFPSQQSPRNEPYVARPS>T<SEI-EDQSMMGKFVKVERQVQDMGKKLDFL | 639 |
KCNQ4 | REKG--D--KG-----------------PS>D<AEVVDEISMMGRVVKVEKQVQSIEHKLDLL | 636 |
KCNQ5 | KKSR--E--KI-----------------TA>E<HETTDDLSMLGRVVKVEKQVQSIESKLDCL | 623 |
KCNA1 | ------------------------------>-<------------------------------ | |
KCNA10 | ------------------------------>-<------------------------------ | |
KCNA2 | ------------------------------>-<------------------------------ | |
KCNA3 | ------------------------------>-<------------------------------ | |
KCNA4 | ------------------------------>-<------------------------------ | |
KCNA5 | ------------------------------>-<------------------------------ | |
KCNA6 | ------------------------------>-<------------------------------ | |
KCNA7 | ------------------------------>-<------------------------------ | |
KCNB1 | ------------------------------>-<------------------------------ | |
KCNB2 | ------------------------------>-<------------------------------ | |
KCNC1 | ------------------------------>-<------------------------------ | |
KCNC2 | ------------------------------>-<------------------------------ | |
KCNC3 | ------------------------------>-<------------------------------ | |
KCNC4 | ------------------------------>-<------------------------------ | |
KCND1 | ------------------------------>-<------------------------------ | |
KCND2 | ------------------------------>-<------------------------------ | |
KCND3 | ------------------------------>-<------------------------------ | |
KCNF1 | ------------------------------>-<------------------------------ | |
KCNG1 | ------------------------------>-<------------------------------ | |
KCNG2 | ------------------------------>-<------------------------------ | |
KCNG3 | ------------------------------>-<------------------------------ | |
KCNG4 | ------------------------------>-<------------------------------ | |
KCNS1 | ------------------------------>-<------------------------------ | |
KCNS2 | ------------------------------>-<------------------------------ | |
KCNS3 | ------------------------------>-<------------------------------ | |
KCNV1 | ------------------------------>-<------------------------------ | |
KCNV2 | ------------------------------>-<------------------------------ | |
cons | > < |
Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
---|---|---|---|---|---|
p.K579N | c.1737G>C | Putative Benign | SIFT: Polyphen: |